At single oral doses of 100 mg and 200 mg, transient dose-relevant impairment of coloration discrimination was detected utilizing the Farnsworth-Munsell a hundred-hue test, with peak results near the time of peak plasma concentrations. This finding is in line with the inhibition of PDE6, which can be associated with phototransduction while in the retina.
are allergic to sildenafil, as contained in VIAGRA and REVATIO, or any with the elements in VIAGRA. See the conclusion of the leaflet for an entire list of ingredients in VIAGRA.
Physicians ought to discuss with people the prospective cardiac hazard of sexual action in people with preexisting cardiovascular possibility elements. People who encounter signs (e.
VIAGRA is often taken with or without foods. If you're taking VIAGRA after a significant fat food (for instance a cheeseburger and french fries), VIAGRA could just take a bit more time to start out Performing
In lots of cases, professional medical comply with-up information and facts was constrained. It is actually impossible to ascertain regardless of whether these claimed situations are similar directly to the usage of VIAGRA, towards the patient's underlying danger elements for hearing loss, a mix of these components, or to other elements [see WARNINGS AND Safety measures and Affected person Details].
In particular, Be sure that you go over if you are working with any of the following check here in advance of using sildenafil.
The AUC in the Energetic metabolite, N-desmethyl sildenafil, was amplified sixty two% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. These results to the metabolite will not be predicted being of scientific consequence.
The safety of VIAGRA is unfamiliar in clients with bleeding Diseases and people with Lively peptic ulceration.
While sildenafil improves some markers of condition in people with pulmonary arterial hypertension, it doesn't appear to have an effect on the chance of Loss of life or severe Uncomfortable side effects.[20]
The commonest side effects of sildenafil are listed down below. These Unwanted side effects may change depending on the ailment that is certainly becoming treated. Tell your healthcare company For those who have any of these Unwanted effects that hassle you.
Should you accidentally choose excessive VIAGRA, simply call your doctor or drop by the closest clinic emergency home at once.
There may be other Negative effects of sildenafil that aren't outlined here. Make contact with your Health care company if you think that you are getting a aspect influence of the medication.
Doctors must advise clients to not get VIAGRA with other PDE5 inhibitors which includes REVATIO or other pulmonary arterial hypertension (PAH) treatments that contains sildenafil.
Doctors must talk about with patients the contraindication of VIAGRA with usage of guanylate cyclase stimulators for example riociguat [see CONTRAINDICATIONS].